KU Leuven

Biosensors group (KUL-MeBioS)

About

The KUL-MeBioS team has extensive experience in microfluidics, advanced microscopy techniques, and microfabrication, with a strong track record of developing innovative lab-on-a-chip systems for biomedical applications. Led by Prof. Jeroen Lammertyn, an internationally recognized expert (>250 internation journal articles, h-index of 71 and (co-)inventor of 12 patents), the team brings unique expertise in designing microfluidic devices for precise cell manipulation, high-throughput analysis, and translating complex laboratory workflows into compact, reliable systems that can be applied in real-world settings in forensics and beyond.

The KUL-MeBioS team is developing two innovative microfluidic tools to isolate male cells from forensic samples and transform forensic DNA analysis. MicroLyseFX streamlines the separation of sperm cells from vaginal cells in post-coital swabs, making it faster, more precise, and less prone to errors. MicroSortFX tackles one of the toughest challenges in the field: isolating rare male cells from complex or low-quality samples. Using on-chip fluorescent tagging and sorting, male cells are automatically separated, even when extremely scarce. By collaborating closely with forensic end-users and industry partners, both tools will be tested with realistic forensic samples and integrated into user-friendly devices. By combining automation, sensitivity, and single-cell precision, these innovations will accelerate investigations, improve detection, and unlock forensic and diagnostic possibilities that were previously out of reach.

Our team

Prof. Jeroen Lammertyn

Full Professor | Team Lead

I am a Full Professor at KU Leuven, Department of Biosystems, Division MeBioS with over 20 years of experience in biosensors, microfluidics, and single-cell analysis. I founded and lead the MeBioS-Biosensors group, also known as Lammertyn lab, where we innovate bio-molecular detection and miniaturized analysis systems with applications in in vitro diagnostics and life-science research. I have authored over 250 peer-reviewed publications, coordinated major EU projects, hold multiple patents and co-founded the FOx Biosystems spin-off.

Dr. Karen Ven

Postdoctoral researcher

I am a Project Manager in the Lammertyn lab at KU Leuven, where I oversee collaborations with academic and industrial partners focused on microfluidic tools for single-cell and spatial analysis across diverse applications, including forensics. I earned my PhD in Bioscience Engineering from KU Leuven in 2020 for developing novel digital bioassay concepts and later pursued postdoctoral research on advanced microfluidic technologies for single-cell screening.

Dr. Iene Rutten

Innovation manager

I am an Innovation Manager at KU Leuven with a PhD in Bioscience Engineering and extensive experience in developing biological-application tailored microfluidic solutions and bioassays. My focus is on the valorisation and translation of novel in vitro diagnostic and life science research tools into impactful, real-world applications.